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The effect of different fertilizing systems on productivity and nutritional uptake from wheat variety Prelom, grown on medaw soil Plovdiv region was studed. The studded fertilizing systems were: 1. unfertilized; 2. N5P7,5K5; 3. N12P7,5K5; 4. N18P7,5K5; 5. 6 manure +NP; 6. N12P0K5; 7. N12P7,5K0. The different fertilizing systems led to different yield increasing from 69.2 to 214.7 % in comparison with unfertilized variant. The nitrogen fertilization had crucial effect on the yield. The exclusion of phosphorus from mineral fertilizing system decreased wheat productivity with 121.8 % in comparison with analogy system but phosphorus ensured. The exclusion of potassium had not effect on wheat productivity. The fertilized plants were taken up from 5.5 to 12.9 kg N/dka, from 1.4 to 4.0 kg P2O5/dka, from 4.4 to 11.8 kg K2O/dka. The wheat variety Prelom up take from 1.73 to 2.97 kg N, from 0.51 to 10.94 kg P2O5 from 1.86 to 2.60 kg K2O for formation of 100 kg main production.